Publications

All our publications are found here (Google Scholar)

(1) 林智広. 機械学習を用いたタンパク質分子の表面構造の統計解析による分類･機能予測 (Beyond コロイド・界面化学×高分子). C & I Communication 2024, 49 (1), 3-5.

(2) 林智広. 機械学習を用いた単分子膜･高分子コーティング膜の設計 (ポリマー探索は AI 活用で勝つよー！). 高分子 2024, 73 (8), 384-385.

(3) 千頭俊太; 前田翔一; 林智広. 赤外吸収分光法と多変量解析を組み合わせた毛髪､ソフトコンタクトレンズの水和状態の解析. 応用物理学会 有機分子・バイオエレクトロニクス分科会会誌 2024.

(4) 高橋誠一郎; 畠山健治; 廣瀬賢一; 林智広; 海津莉子. 細胞培養用基材の表面構造及び細胞培養チップ. 2024.

(5) Tran, G.-S.; Chen, C.-J.; Maeda, S.; Chikami, S.; Hayashi, T.; Chiang, C.-Y. Tuning selectivity toward three-carbon product of glycerol electrooxidation in borate buffer through manipulating borate/glycerol molar ratio. Journal of Catalysis 2024, 438. DOI: 10.1016/j.jcat.2024.115715.

(6) Sotani, T.; Otoba, M.; Hosotani, M.; Hayashi, T.; Sogawa, H.; Sanda, F. Bipyridine-containing π-conjugated polymers bearing optically active amide groups: mechanistic aspects of formation of chiral higher-order structures. Polymer Chemistry 2024, 15 (9), 915-923. DOI: 10.1039/d3py01374j.

(7) Seong, S.; Kang, H.; Kim, H.; Son, Y. J.; Jang, J.; Maeda, S.; Chikami, S.; Hayashi, T.; Yoon, H. J.; Noh, J. Effects of the substituent position on the structural order, work function change, and thermopower of dichloro-substituted benzenethiolate self-assembled monolayers on Au (1 1 1). Applied Surface Science 2024, 643, 158661.

(8) Seo, D.; Seong, S.; Kim, H.; Oh, H. S.; Lee, J. H.; Kim, H.; Kim, Y. O.; Maeda, S.; Chikami, S.; Hayashi, T.; et al. Molecular Self-Assembly and Adsorption Structure of 2,2′-Dipyrimidyl Disulfides on Au(111) Surfaces. Molecules 2024, 29 (4). DOI: 10.3390/molecules29040846  From NLM PubMed-not-MEDLINE.

(9) Pham, M.-T. H.; Yao, A. A. W.; Vo, T.-G.; Hayashi, T.; Chiang, C.-Y. Unlocking the Potential of Mixed-valence Silver Oxide for Electrochemical Valorization of 5-hydroxymethylfurfural into Valuable Products. Materials Today Sustainability 2024.

(10) Noh, J.; Lee, J. H.; Han, J. W.; Lee, G.; Han, S.; Kim, H.; Seo, D.; Kaizu, R.; Latag, G. V.; Hayashi, T. Effect of anchoring groups on the formation of self-assembled monolayers on Au(111) from cyclohexanethiol and cyclohexyl thiocyanate. Thin Solid Films 2024.

(11) Moon, J.; Hu, G.; Hayashi, T. Application of Machine Learning in the Quantitative Analysis of the Surface Characteristics of Highly Abundant Cytoplasmic Proteins: Toward AI-Based Biomimetics. Biomimetics (Basel) 2024, 9 (3), 162. DOI: 10.3390/biomimetics9030162  From NLM PubMed-not-MEDLINE.

(12) Kamimura, R.; Maeda, S.; Hayashi, T.; Motobayashi, K.; Ikeda, K. Why Is Surface-Enhanced Raman Scattering Insensitive to Liquid Water? J Am Chem Soc 2024, 146 (32), 22327-22334. DOI: 10.1021/jacs.4c04901  From NLM PubMed-not-MEDLINE.

(13) Hu, G.; Moon, J.; Hayashi, T. Protein Classes Predicted by Molecular Surface Chemical Features: Machine Learning-Assisted Classification of Cytosol and Secreted Proteins. J Phys Chem B 2024, 128 (35), 8423-8436. DOI: 10.1021/acs.jpcb.4c02461  From NLM Medline.

(14) Hayashi, T. Design of Biomaterials Using Informatics. In Drug Development Supported by Informatics, Satoh, H., Funatsu, K., Yamamoto, H. Eds.; Springer, 2024.

(15) Chikami, S.; Maeda, S.; Latag, G. V.; Kaizu, R.; Tanji, N.; Ezure, M.; Nagase, S.; Hayashi, T. Analysis of the hydration water on the surface of human hair using a combination of infrared absorption vibrational spectroscopy and multivariate curve resolution. Surface and Interface Analysis 2024, 56 (8), 580-586. DOI: 10.1002/sia.7316.

(16) 林智広. 材料表面への生体分子の吸着と機械学習を用いた吸着の予測. In 吸着技術の産業応用~基礎知識･吸着剤の特性･技術応用事例, 情報機構, 2023; pp 313-322.

(17) 徳田英幸; 林智広. 研究機関トップからのメッセージ――さまざまな分野の研究者間で刺激し合い, ワクワクする研究機関――情報通信研究機構 (NICT) の将来ビジョンと若手研究者の育成について. 応用物理 2023, 92 (10), 584-587.

(18) 前田翔一; 千頭俊太; 林智広. 赤外吸収分光と多変量解析の融合による界面選択的分光. Jasco Report 2023, 65 (2), 48-51.

(19) Son, Y. J.; Han, J. W.; Kang, H.; Seong, S.; Han, S.; Maeda, S.; Chikami, S.; Hayashi, T.; Hara, M.; Noh, J. Formation and Thermal Stability of Ordered Self-Assembled Monolayers by the Adsorption of Amide-Containing Alkanethiols on Au(111). Int J Mol Sci 2023, 24 (4). DOI: 10.3390/ijms24043241  From NLM Medline.

(20) Rajapriya Inbaraj, N.; Song, S.; Chang, R.; Fujita, K.; Hayashi, T. Investigation of Hydration States of Ionic Liquids by Fourier Transform Infrared Absorption Spectroscopy: Relevance to Stabilization of Protein Molecules. Langmuir 2023, 39 (7), 2558-2568. DOI: 10.1021/acs.langmuir.2c02851  From NLM Medline.

(21) Latag, G. V.; Nakamura, T.; Palai, D.; Mondarte, E. A. Q.; Hayashi, T. Investigation of Three-Dimensional Bacterial Adhesion Manner on Model Organic Surfaces Using Quartz Crystal Microbalance with Energy Dissipation Monitoring. ACS Appl Bio Mater 2023, 6 (3), 1185-1194. DOI: 10.1021/acsabm.2c01012  From NLM Medline.

(22) Hayashi, T. Surface Coatings that Repel Biomolecules and Cells: Molecular-Level Mechanisms of Bio-Stealthiness and Material Design Using Informatics. Journal of the Japan Society of Colour Material 2023, 96 (8), 261-265. DOI: 10.4011/shikizai.96.261.

(23) 林智広; 松田智昌; 一色綾子. 分光法による界面領域の測定方法. 2022.

(24) 林智広. 情報科学を用いた生体適合性単分子膜・高分子コーティングの設計. 成形加工 2022, 34 (11), 398-401.

(25) 林智広. 表面・界面・情報科学の融合による抗付着性コーティング材料の設計. 日本金属学会会報｢まてりあ｣ 2022, 61 (11), 1-4.

(26) 林智広. 表面科学の手法を用いたバイオマテリアル近傍の水の解析. 電子情報通信学会技術研究報告 2022, 121 (371), 7-10.

(27) 林智広. バイオマテリアル解析のための表面科学的手法; 情報機構 2022.

(28) 林智広. 表面・界面科学の手法による生体分子・細胞と人工材料の界面の分子プロセスの解析. バイオマテリアル－生体材料－ 2022, 40 (1), 38.

(29) Song, S.; Latag, G. V.; Mondarte, E. A. Q.; Chang, R.; Hayashi, T. Experimental Characterization of Water Condensation Processes on Self-Assembled Monolayers Using a Quartz Crystal Microbalance with Energy Dissipation Monitoring. Micro 2022, 2 (3), 513-523. DOI: 10.3390/micro2030033.

(30) Seong, S.; Kang, H.; Han, S.; Son, Y. J.; Jang, J.; Yoon, H. J.; Maeda, S.; Song, S.; Palai, D.; Hayashi, T.; et al. Surface structure and work function change of pentafluorobenzeneselenolate self-assembled monolayers on Au (111). Surfaces and Interfaces 2022, 33. DOI: 10.1016/j.surfin.2022.102228.

(31) Palai, D.; 千頭俊太; 前田翔一; 田原寛之; 林智広. 機械学習を用いたバイオインターフェースの設計: 単分子膜を用いた検証から高分子膜への展開. 表面と真空 2022, 65 (1), 10-14.

(32) Palai, D.; Tahara, H.; Chikami, S.; Latag, G. V.; Maeda, S.; Komura, C.; Kurioka, H.; Hayashi, T. Prediction of Serum Adsorption onto Polymer Brush Films by Machine Learning. ACS Biomater Sci Eng 2022, 8 (9), 3765-3772. DOI: 10.1021/acsbiomaterials.2c00441  From NLM Medline.

(33) Mondarte, E. A. Q.; Zamarripa, E. M. M.; Chang, R.; Wang, F.; Song, S.; Tahara, H.; Hayashi, T. Interphase Protein Layers Formed on Self-Assembled Monolayers in Crowded Biological Environments: Analysis by Surface Force and Quartz Crystal Microbalance Measurements. Langmuir 2022, 38 (4), 1324-1333. DOI: 10.1021/acs.langmuir.1c02312  From NLM Medline.

(34) Maeda, S.; Chikami, S.; Latag, G. V.; Song, S.; Iwakiri, N.; Hayashi, T. Analysis of Vicinal Water in Soft Contact Lenses Using a Combination of Infrared Absorption Spectroscopy and Multivariate Curve Resolution. Molecules 2022, 27 (7). DOI: 10.3390/molecules27072130  From NLM Medline.

(35) Kang, H.; Jeong, H.; Seong, S.; Han, S.; Ji Son, Y.; Tahara, H.; Hayashi, T.; Jae Yoon, H.; Noh, J. Formation and superlattice of long-range and highly ordered alicyclic selenolate monolayers on Au(1 1 1) studied by scanning tunneling microscopy. Applied Surface Science 2022, 572. DOI: 10.1016/j.apsusc.2021.151454.

(36) Arai, Y.; Hayashi, T. Characterization of Polymerized Layer of Alkylsilane on Surfaces of Silica Filler Materials by Force Spectroscopic Measurements Using Atomic Force Microscope. Sensors and Materials 2022, 34 (11), 3959-3965. DOI: 10.18494/sam4101.

(37) 林智広. AIを用いたバイオマテリアルの設計. 工業材料 (日刊工業新聞社) 2021, 69 (8), 59.

(38) Tanaka, M.; Morita, S.; Hayashi, T. Role of interfacial water in determining the interactions of proteins and cells with hydrated materials. Colloids Surf B Biointerfaces 2021, 198, 111449. DOI: 10.1016/j.colsurfb.2020.111449  From NLM Medline.

(39) Shimosaraya, N.; Sotani, T.; Miyagi, Y.; Mondarte, E. A. Q.; Suthiwanich, K.; Hayashi, T.; Nagata, Y.; Sogawa, H.; Sanda, F. Tyrosine-based photoluminescent diketopiperazine supramolecular aggregates. Soft Matter 2021, 18 (1), 137-145. DOI: 10.1039/d1sm01206a  From NLM Medline.

(40) Nakamura, T.; Mondarte, E. A. Q.; Tahara, H.; Chang, R.; Hayashi, T. Chemical force spectroscopic mapping of nanoparticle-embedded polyester fiber by atomic force microscopy. Molecular Crystals and Liquid Crystals 2021, 728 (1), 52-58. DOI: 10.1080/15421406.2021.1946977.

(41) Mondarte, E. A. Q.; Tahara, H.; Suthiwanich, K.; Song, S.; Wang, F.; Hayashi, T. Lab on a Tip: Atomic Force Microscopy as a Versatile Analytical Tool for Nano-bioscience. Sensors and Materials 2021, 33 (1), 223-232. DOI: 10.18494/sam.2021.3069.

(42) Maekawa, T.; Nyu, T.; Mondarte, E. A. Q.; Tahara, H.; Suthiwanich, K.; Hayashi, T. Visualization of molecular binding sites at the nanoscale in the lift-up mode by amplitude-modulation atomic force microscopy. Nanoscale 2021, 13 (7), 4213-4220. DOI: 10.1039/d0nr06125e  From NLM PubMed-not-MEDLINE.

(43) Hayashi, T. Water at Interfaces: Its Behavior and Roles in Interfacial Phenomena. Chemistry Letters 2021, 50 (6), 1173-1180. DOI: 10.1246/cl.210049.

(44) Czajor, J.; Abuillan, W.; Nguyen, D.-V.; Heidebrecht, C.; Mondarte, E. A.; Konovalov, O.; Hayashi, T.; Felder-Flesch, D.; Kaufmann, S.; Tanaka, M. Dendronized Oligoethylene Glycols with Posphonate Tweezers for Cell-Repellent Coating of Oxide Surfaces: Coarse-Scale and Nanoscopic Interfacial Forces. RSC Advances 2021, 11, 17727-17733.

(45) Chang, R.; Quimada Mondarte, E. A.; Palai, D.; Sekine, T.; Kashiwazaki, A.; Murakami, D.; Tanaka, M.; Hayashi, T. Protein- and Cell-Resistance of Zwitterionic Peptide-Based Self-Assembled Monolayers: Anti-Biofouling Tests and Surface Force Analysis. Front Chem 2021, 9, 748017. DOI: 10.3389/fchem.2021.748017  From NLM PubMed-not-MEDLINE.

(46) Bai, M. Y.; Ku, F. Y.; Shyu, J. F.; Hayashi, T.; Wu, C. C. Evaluation of Polyacrylonitrile Nonwoven Mats and Silver-Gold Bimetallic Nanoparticle-Decorated Nonwoven Mats for Potential Promotion of Wound Healing In Vitro and In Vivo and Bone Growth In Vitro. Polymers (Basel) 2021, 13 (4). DOI: 10.3390/polym13040516  From NLM PubMed-not-MEDLINE.

(47) 林智広. 原子間力顕微鏡を用いたバイオ界面の解析: 水中での評価技術の発展と代表的成果. In 水中・液中における測定・評価と応用技術, 2020.

(48) 林智広. データ科学で医療材料を創る. In みらいぶっく〜学問・大学なび 学校法人河合塾, 2020.

(49) 林智広. 材料科学と情報科学の出会い: バイオマテリアル分野の現状. 研究開発リーダー 2020, 16 (10), 22-25.

(50) Suthiwanich, K.; Hiraguchi, Y.; Nyu, T.; Mondarte, E. A. Q.; Takai, M.; Hayashi, T. Imaging nanophase-separated structure of block copolymer by atomic force microscopy in water. Chemistry Letters 2020, 49 (6), 641-644.

(51) Mondarte, E. A.; 田原寛之; 張嶺碩; 林智広. 原子間力顕微鏡を用いた生体分子の特異的結合の解析. 応用物理 2020, 89 (7), 390-393.

(52) Lu, Z.; Mondarte, E. A. Q.; Suthiwanich, K.; Hayashi, T.; Masuda, T.; Isu, N.; Takai, M. Study on Bacterial Antiadhesiveness of Stiffness and Thickness Tunable Cross-Linked Phospholipid Copolymer Thin-Film. ACS Appl Bio Mater 2020, 3 (2), 1079-1087. DOI: 10.1021/acsabm.9b01041  From NLM PubMed-not-MEDLINE.

(53) Liu, C.; Hirohara, M.; Maekawa, T.; Chang, R.; Hayashi, T.; Chiang, C.-Y. Selective electro-oxidation of glycerol to dihydroxyacetone by a non-precious electrocatalyst – CuO. Applied Catalysis B: Environmental 2020, 265, 118543. DOI: 10.1016/j.apcatb.2019.118543.

(54) Kwaria, R. J.; Mondarte, E. A. Q.; Tahara, H.; Chang, R.; Hayashi, T. Data-Driven Prediction of Protein Adsorption on Self-Assembled Monolayers toward Material Screening and Design. ACS Biomater Sci Eng 2020, 6 (9), 4949-4956. DOI: 10.1021/acsbiomaterials.0c01008  From NLM Medline.

(55) Kudo, H.; Naritomi, K.; Onishi, S.; Maekawa, H.; Mondarte, E. A. Q.; Suthiwanich, K.; Hayashi, T. Living Ring-Expansion Polymerization of Thiirane with Cyclic Monocarbamothioates. Macromolecules 2020, 53 (12), 4733-4740. DOI: 10.1021/acs.macromol.0c00687.

(56) Han, S.; Seong, S.; Son, Y. J.; Yokota, Y.; Hayashi, T.; Hara, M.; Noh, J. Formation and Surface Structures of Highly Ordered Self-Assembled Monolayers of Alkyl Selenocyanates on Au(111) via Ambient-Pressure Vapor Deposition. The Journal of Physical Chemistry C 2020, 124 (49), 26730-26740. DOI: 10.1021/acs.jpcc.0c07401.

(57) Choi, Y.; Seong, S.; Han, S.; Son, Y. J.; Mondarte, E. A. Q.; Tahara, H.; Song, S.; Hayashi, T.; Noh, J. Scanning tunneling microscopy study on phase behavior of self-assembled monolayers formed by coadsorption of octanethiol and octyl thiocyanate on Au(111). Thin Solid Films 2020, 707. DOI: 10.1016/j.tsf.2020.138100.

(58) Chang, R.; Mondarte, E. A. Q.; Mendoza Zamarripa, E. M.; Tahara, H.; Hayashi, T. Anti-biofouling Surfaces Made of Biomolecules. Vacuum and Surface Science 2020, 63 (6), 289-293. DOI: 10.1380/vss.63.289.

(59) 林智広; 張嶺碩; Kwaria, R. J.; 田原寛之. 情報科学を用いたバイオマテリアルの設計. 有機分子・バイオエレクトロニクス分科会会誌 2019, 30 (4), 228-233.

(60) 田原寛之; ルドルフ・ジェイソン・クアリア; 林智広. データ駆動的抗タンパク質吸着・抗細胞接着表面設計: 情報科学を用いたバイオマテリアルデザインへの挑戦. 表面と真空 2019, 62 (3), 141-146.

(61) ルドルフ・ジェイソン・クアリア; 田原寛之; 張嶺碩; 林智広. 情報科学を用いたバイオマテリアル設計の可能性. バイオマテリアル-生体材料- 2019, 37 (4), 238-243.

(62) Tsunoi, A.; Lkhamsuren, G.; Mondarte, E. A. Q.; Asatyas, S.; Oguchi, M.; Noh, J.; Hayashi, T. Improvement of the Thermal Stability of Self-Assembled Monolayers of Isocyanide Derivatives on Gold. The Journal of Physical Chemistry C 2019, 123 (22), 13681-13686. DOI: 10.1021/acs.jpcc.9b02256.

(63) Takano, K.; Nyu, T.; Maekawa, T.; Seki, T.; Nakatani, R.; Komamura, T.; Hayakawa, T.; Hayashi, T. Real-time and in situ observation of structural evolution of giant block copolymer thin film under solvent vapor annealing by atomic force microscopy. RSC Adv 2019, 10 (1), 70-75. DOI: 10.1039/c9ra09043f  From NLM PubMed-not-MEDLINE.

(64) Son, Y. J.; Han, S.; Yoshizawa, K.; Hayashi, T.; Hara, M.; Noh, J. Displacement Processes of 1-Adamanetanethiol Self-Assembled Monolayers on Au(111) by 1-Hexanethiol. J Nanosci Nanotechnol 2019, 19 (8), 4732-4735. DOI: 10.1166/jnn.2019.16705  From NLM PubMed-not-MEDLINE.

(65) Park, T.; Kang, H.; Seong, S.; Han, S.; Son, Y. J.; Ito, E.; Hayashi, T.; Hara, M.; Noh, J. Formation and Structure of Highly Ordered Self-Assembled Monolayers by Adsorption of Acetyl-Protected Conjugated Thiols on Au(111) in Tetrabutylammonium Cyanide Solution. The Journal of Physical Chemistry C 2019, 123 (14), 9096-9104. DOI: 10.1021/acs.jpcc.9b00521.

(66) Mondarte, E. A.; Maekawa, T.; Nyu, T.; Tahara, H.; Lkhamsuren, G.; Hayashi, T. Detection of streptavidin-biotin intermediate metastable states at the single-molecule level using high temporal-resolution atomic force microscopy. RSC Adv 2019, 9 (39), 22705-22712. DOI: 10.1039/c9ra04106k  From NLM PubMed-not-MEDLINE.

(67) Mochizuki, M.; Sato, S.; Asatyas, S.; Lesnikowski, Z. J.; Hayashi, T.; Nakamura, H. Raman cell imaging with boron cluster molecules conjugated with biomolecules. RSC Adv 2019, 9 (41), 23973-23978. DOI: 10.1039/c9ra04228h  From NLM PubMed-not-MEDLINE.

(68) Maekawa, T.; Chin, H.; Nyu, T.; Sut, T. N.; Ferhan, A. R.; Hayashi, T.; Cho, N. J. Molecular diffusion and nano-mechanical properties of multi-phase supported lipid bilayers. Phys Chem Chem Phys 2019, 21 (30), 16686-16693. DOI: 10.1039/c9cp02085c  From NLM Medline.

(69) Hirohara, M.; Maekawa, T.; Mondarte, E. A. Q.; Nyu, T.; Mizushita, Y.; Hayashi, T. Proteomic Analysis of Biomaterial Surfaces after Contacting with Body Fluids by MALDI-ToF Mass Spectroscopy. Coatings 2019, 10 (1), 12. DOI: 10.3390/coatings10010012.

(70) Han, S.; Park, H.; Han, J. W.; Yoshizawa, K.; Hayashi, T.; Hara, M.; Noh, J. Solvent Effect on the Formation of Octaneselenocyanate Self-Assembled Monolayers on Au(111). J Nanosci Nanotechnol 2019, 19 (8), 4795-4798. DOI: 10.1166/jnn.2019.16706  From NLM PubMed-not-MEDLINE.

(71) Choi, Y.; Seong, S.; Son, Y. J.; Han, S.; Ito, E.; Mondarte, E. A. Q.; Chang, R.; Hayashi, T.; Hara, M.; Noh, J. Formation of long-range-ordered self-assembled monolayers of dodecyl thiocyanates on Au(111) via ambient-pressure vapor deposition. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2019, 583. DOI: 10.1016/j.colsurfa.2019.123969.

(72) Chen, H. Y.; Hayashi, T.; Koenig, M.; Lai, J. J. Editorial: Polymer Surface Chemistry: Biomolecular Engineering and Biointerfaces. Front Chem 2019, 7, 271. DOI: 10.3389/fchem.2019.00271  From NLM PubMed-not-MEDLINE.

(73) Asai, T.; Liu, H.; Ozeki, Y.; Sato, S.; Hayashi, T.; Nakamura, H. Imaging of cellular uptake of boron cluster compound by stimulated Raman scattering microscopy. Applied Physics Express 2019, 12 (11), 112004. DOI: 10.7567/1882-0786/ab4a5d.

(74) 林智広. [談話室] 林研究室の紹介: 研究内容・研究室内コミュニケーションについて. 応用物理学会 薄膜・表面物理分科会 News Letter 2018, 162, 40-44.

(75) 田原寛之; Kwaria, R. J.; 林智広. マテリアルズ・インフォマティクス～データ科学と計算・実験の融合による材料開発～ 第8節 「マテリアルズ・インフォマティクスを用いたバイオマテリアルの設計の現状と今後の展開; 情報機構, 2018.

(76) 田原寛之; Kwaria, R. J.; 林智広. 「マテリアルズ・インフォマティクス」の1節 「マテリアルズインフォマティクスによる生体材料表面設計」; 技術情報協会, 2018.

(77) Tahara, H.; Nyu, T.; Mondarte, E. A. Q.; Maekawa, T.; Hayashi, T. Application of Fuzzy Logic Algorithm to Single-Molecule Force Spectroscopy of the Streptavidin-Biotin System. Advances in Materials Physics and Chemistry 2018, 08 (05), 217-226. DOI: 10.4236/ampc.2018.85014.

(78) Sung, T.; Seong, S.; Han, S.; Son, Y. J.; Ishida, T.; Hayashi, T.; Hara, M.; Noh, J. Well-Ordered Domains of 4-Fluorobenzenethiol Self-Assembled Monolayers on Au(111) Guided by a Displacement Reaction. J Nanosci Nanotechnol 2018, 18 (10), 7053-7057. DOI: 10.1166/jnn.2018.15501  From NLM PubMed-not-MEDLINE.

(79) Sekine, T.; Kanayama, N.; Ozasa, K.; Nyu, T.; Hayashi, T.; Maeda, M. Stochastic Binding Process of Blunt-End Stacking of DNA Molecules Observed by Atomic Force Microscopy. Langmuir 2018, 34 (49), 15078-15083. DOI: 10.1021/acs.langmuir.8b02224  From NLM Medline.

(80) Hamamoto, R.; Ito, H.; Hirohara, M.; Chang, R.; Hongo-Hirasaki, T.; Hayashi, T. Interactions between protein molecules and the virus removal membrane surface: Effects of immunoglobulin G adsorption and conformational changes on filter performance. Biotechnol Prog 2018, 34 (2), 379-386. DOI: 10.1002/btpr.2586  From NLM Medline.

(81) Chang, R.; Asatyas, S.; Lkhamsuren, G.; Hirohara, M.; Mondarte, E. A. Q.; Suthiwanich, K.; Sekine, T.; Hayashi, T. Water near bioinert self-assembled monolayers. Polymer Journal 2018, 50 (8), 563-571. DOI: 10.1038/s41428-018-0075-1.

(82) Araki, Y.; Sekine, T.; Chang, R.; Hayashi, T.; Onishi, H. Molecular-scale structures of the surface and hydration shell of bioinert mixed-charged self-assembled monolayers investigated by frequency modulation atomic force microscopy. RSC Adv 2018, 8 (43), 24660-24664. DOI: 10.1039/c8ra03569e  From NLM PubMed-not-MEDLINE.

(83) 張嶺碩; 関根泰斗; Asatyas, S.; Lkhamsuren, G.; 大橋智幸; 林智広. 生体適合性をもつ単分子膜~表面・界面科学の手法を利用したメカニズムの解明~. 化学工業 2017, 68 (12), 886-890.

(84) Seong, S.; Kang, H.; Han, S.; Sung, T.; Park, J. B.; Hayashi, T.; Hara, M.; Noh, J. Formation and Structural Changes of 4-Fluorobenzenethiol Self-Assembled Monolayers on Au(111). Journal of Nanoscience and Nanotechnology 2017, 17 (8), 5597-5600. DOI: 10.1166/jnn.2017.14162.

(85) Sekine, T.; Asatyas, S.; Sato, C.; Morita, S.; Tanaka, M.; Hayashi, T. Surface force and vibrational spectroscopic analyses of interfacial water molecules in the vicinity of methoxy-tri(ethylene glycol)-terminated monolayers: mechanisms underlying the effect of lateral packing density on bioinertness. J Biomater Sci Polym Ed 2017, 28 (10-12), 1231-1243. DOI: 10.1080/09205063.2017.1303120  From NLM Medline.

(86) Mochizuki, M.; Lkhamsuren, G.; Suthiwanich, K.; Mondarte, E. A.; Yano, T. A.; Hara, M.; Hayashi, T. Damage-free tip-enhanced Raman spectroscopy for heat-sensitive materials. Nanoscale 2017, 9 (30), 10715-10720. DOI: 10.1039/c7nr02398g  From NLM PubMed-not-MEDLINE.

(87) Lkhamsuren, G.; Mochizuki, M.; Suthiwanich, K.; Hayashi, T. Fabrication of mechanically stable Au-coatings on probes of atomic force microscopes for nano-mechanical and -optical measurements. Thin Solid Films 2017, 636, 478-484. DOI: 10.1016/j.tsf.2017.06.046.

(88) Hara, K.; Yano, T. A.; Suzuki, K.; Hirayama, M.; Hayashi, T.; Kanno, R.; Hara, M. Raman Imaging Analysis of Local Crystal Structures in LiCoO(2) Thin Films Calcined at Different Temperatures. Anal Sci 2017, 33 (7), 853-858. DOI: 10.2116/analsci.33.853  From NLM PubMed-not-MEDLINE.

(89) Han, M.-S.; Ku, K.; Kang, H.; Ohashi, R.; Hayashi, T.; Hara, M.; Noh, J. Standing-Up Phase of Hexanedithiol Self-Assembled Monolayers on Au(111) Induced by Displacement Reaction. Journal of Nanoscience and Nanotechnology 2017, 17 (8), 5780-5783. DOI: 10.1166/jnn.2017.14163.

(90) Yano, T.-a.; Tsuchimoto, Y.; Mochizuki, M.; Hayashi, T.; Hara, M. Laser-scanning-assisted tip-enhanced optical microscopy for robust optical nano-spectroscopy. Applied Spectroscopy 2016, 70 (7), 1239-1243.

(91) Tsuchimoto, Y.; Yano, T. A.; Hayashi, T.; Hara, M. Fano resonant all-dielectric core/shell nanoparticles with ultrahigh scattering directionality in the visible region. Opt Express 2016, 24 (13), 14451-14462. DOI: 10.1364/OE.24.014451  From NLM PubMed-not-MEDLINE.

(92) Mochizuki, M.; Asatyas, S.; Suthiwanich, K.; Hayashi, T. Thiol Molecules as Temperature Sensors for Surface-enhanced Raman Scattering Measurements of Heat-sensitive Materials. Chemistry Letters 2016, 45 (10), 1207-1209. DOI: 10.1246/cl.160572.

(93) Kim, Y.; Kang, H.; Tsunoi, A.; Hayashi, T.; Hara, M.; Noh, J. Striped Phase of 3-Hexylthiophene Self-Assembled Monolayers on Au(111) from Vapor Phase Deposition. Journal of Nanoscience and Nanotechnology 2016, 16 (3), 2792-2795.

(94) Kim, S. O.; Jackman, J. A.; Mochizuki, M.; Yoon, B. K.; Hayashi, T.; Cho, N. J. Correlating single-molecule and ensemble-average measurements of peptide adsorption onto different inorganic materials. Phys Chem Chem Phys 2016, 18 (21), 14454-14459. DOI: 10.1039/c6cp01168c  From NLM Medline.

(95) Kang, H.; Ito, E.; Hayashi, T.; Hara, M.; Noh, J. Effect of Solution Concentration on the Formation of Ordered Domains in Pentachlorobenzenethiol Self-Assembled Monolayers on Au(111). J Nanosci Nanotechnol 2016, 16 (6), 6360-6363. DOI: 10.1166/jnn.2016.12115  From NLM Medline.

(96) Kanayama, N.; Sekine, T.; Ozasa, K.; Kishi, S.; Nyu, T.; Hayashi, T.; Maeda, M. Terminal-Specific Interaction between Double-Stranded DNA Layers: Colloidal Dispersion Behavior and Surface Force. Langmuir 2016, 32 (49), 13296-13304. DOI: 10.1021/acs.langmuir.6b03470  From NLM Medline.

(97) Jeong, H.; Kang, H.; Han, S.; Park, H.; Han, J.; Hayashi, T.; Hara, M.; Noh, J. Comparative Study for Displacement of Cyclohexanethiolate and Cyclohaxaneselenolate Self-Assembled Monolayers on Au(111) by Octanethiols. Journal of Nanoscience and Nanotechnology 2016, 16 (8), 8508-8512. DOI: 10.1166/jnn.2016.12531.

(98) Han, S.; Kang, H.; Park, J. B.; Hayashi, T.; Hara, M.; Noh, J. Formation and Structure of Self-Assembled Monolayers by Adsorption of Octaneselenocyanate on Au(111). Journal of Nanoscience and Nanotechnology 2016, 16 (8), 8610-8613. DOI: 10.1166/jnn.2016.12509.

(99) Ganbaatar, N.; Matsuzaki, N.; Nakazawa, Y.; Afrin, R.; Aono, M.; Yano, T.-a.; Hayashi, T.; Hara, M. Surface Force Analysis of Pyrite (FeS<sub>2</sub>): Its Reactivity to Amino Acid Adsorption. Advances in Materials Physics and Chemistry 2016, 06 (07), 167-176. DOI: 10.4236/ampc.2016.67018.

(100) 関根泰斗; Asatyas, S.; 丹生隆; Lkhamsuren, G.; 角井杏帆; 佐藤千香子; 森田成昭; 田中賢; 林智広. 単分子膜における生体不活性特性のメカニズム: 分子集積密度の界面水分子の振る舞いへの影響

. 表面科学 2015, 36 (8), 424-429.

(101) Yano, T.-a.; Yoshida, K.; Hayamizu, Y.; Hayashi, T.; Ohuchi, F.; Hara, M. Probing edge-activated resonant Raman scattering from mechanically exfoliated 2D MoO

3

nanolayers. 2D Materials 2015, 2 (3), 035004. DOI: 10.1088/2053-1583/2/3/035004.

(102) Tsuchimoto, Y.; Yano, T. A.; Hada, M.; Nakamura, K. G.; Hayashi, T.; Hara, M. Controlling the Visible Electromagnetic Resonances of Si/SiO2 Dielectric Core-Shell Nanoparticles by Thermal Oxidation. Small 2015, 11 (37), 4844-4849. DOI: 10.1002/smll.201500884  From NLM PubMed-not-MEDLINE.

(103) Sekine, T.; Tanaka, Y.; Sato, C.; Tanaka, M.; Hayashi, T. Evaluation of Factors To Determine Platelet Compatibility by Using Self-Assembled Monolayers with a Chemical Gradient. Langmuir 2015, 31 (25), 7100-7105. DOI: 10.1021/acs.langmuir.5b01216  From NLM Medline.

(104) Mochizuki, M.; Oguchi, M.; Kim, S. O.; Jackman, J. A.; Ogawa, T.; Lkhamsuren, G.; Cho, N. J.; Hayashi, T. Quantitative Evaluation of Peptide-Material Interactions by a Force Mapping Method: Guidelines for Surface Modification. Langmuir 2015, 31 (29), 8006-8012. DOI: 10.1021/acs.langmuir.5b01691  From NLM Medline.

(105) Kudo, H.; Shizuma, M.; Kubo, K.; Hayashi, T. Calixarene-polymers via Simple Polymerization of t-Butylcalix[8]arenes (A8-type Monomer) with Hexamethylene Diisocyanate (B2-type Monomer); Molecular Bunch of Grapes (Botryosin). Chemistry Letters 2015, 44 (12), 1765-1767. DOI: 10.1246/cl.150840.

(106) Balois, M. V.; Hayazawa, N.; Catalan, F. C.; Kawata, S.; Yano, T. A.; Hayashi, T. Tip-enhanced THz Raman spectroscopy for local temperature determination at the nanoscale. Anal Bioanal Chem 2015, 407 (27), 8205-8213. DOI: 10.1007/s00216-015-8866-0  From NLM PubMed-not-MEDLINE.

(107) 林智広. 表面科学の基礎 (現代表面科学シリーズ 2); 共立出版, 2014.

(108) 林智広. 走査型プローブ顕微鏡によるバイオマテリアルの解析. In 生体適合性制御と要求特性掌握から実践する高分子バイオマテリアルの設計・開発戦略

～モノマー（いち）からデザインするバイオインターフェースと上市までの道筋～, サイエンス&テクノロジー, 2014.

(109) 由二, 蓜.; 智広, 林.; 晶夫, 岸.; 成昭, 森.; 裕一, 大.; 健次, 石.; 賢, 田.; 誠人, 大.; 慎吾, 小.; 竜介, 中.; et al. 生体適合性制御と要求特性掌握から実践する高分子バイオマテリアルの設計・開発戦略～モノマー（いち）からデザインするバイオインターフェースと上市までの道筋～; サイエンス&テクノロジー, 2014.

(110) 田中賢; 林智広; 森田成昭. 血液適合性に優れた高分子材料の水和状態. バイオマテリアル 2014, 32 (2), 74-85.

(111) Portela, A.; Yano, T.; Santschi, C.; Matsui, H.; Hayashi, T.; Hara, M.; Martin, O. J. F.; Tabata, H. Spectral tunability of realistic plasmonic nanoantennas. Applied Physics Letters 2014, 105 (9), 91105-91110. DOI: 10.1063/1.4894633.

(112) Oguchi, M.; Mochizuki, M.; Yano, T.-a.; Hara, M.; Hayashi, T. Light-transmittable Ultrasmooth Gold Film for Gap-mode Tip-enhanced Raman Scattering Spectroscopy. Chemistry Letters 2014, 43 (6), 808-810. DOI: 10.1246/cl.140093.

(113) Hiraguchi, Y.; Nagahashi, K.; Shibayama, T.; Hayashi, T.; Yano, T. A.; Kushiro, K.; Takai, M. Effect of the distribution of adsorbed proteins on cellular adhesion behaviors using surfaces of nanoscale phase-reversed amphiphilic block copolymers. Acta Biomater 2014, 10 (7), 2988-2995. DOI: 10.1016/j.actbio.2014.03.019  From NLM Medline.

(114) 林智広. 生体不活性特性における水分子の役割. C & I Commun 2013, 38 (2), 17-18.

(115) 小出裕基; 久保光亮; 関根泰斗; 水下佳紀; Ganbaatar, N.; 林智広. 原子間力顕微鏡を用いた生体不活性表面近傍の水分子の解析. 表面科学 2013, 34 (9), 494-499.

(116) Tanaka, M.; Hayashi, T.; Morita, S. The roles of water molecules at the biointerface of medical polymers. Polymer Journal 2013, 45 (7), 701-710. DOI: 10.1038/pj.2012.229.

(117) Tanaka, M.; Mabuchi, Y.; Hayashi, T.; Hara, M. Subtractive offset printing for fabrication of sub micrometer scale electrodes with gold nanoparticles. Microelectronic Engineering 2012, 95 (15), 14-20. DOI: 10.1016/j.mee.2012.02.023.

(118) Kumashiro, Y.; Ikezoe, Y.; Hayashi, T.; Okabayashi, Y.; Tamada, K.; Yamato, M.; Okano, T.; Hara, M. Temperature-modulated adsorption of poly(N-isopropylacrylamide)-grafted ferritin on solid substrate. Colloids Surf B Biointerfaces 2012, 95, 57-64, Research Support, Non-U.S. Gov’t. DOI: 10.1016/j.colsurfb.2012.02.028  From NLM Medline.

(119) Ito, E.; Ito, H.; Kang, H.; Hayashi, T.; Hara, M.; Noh, J. Influence of Surface Morphology and Substrate on Thermal Stability and Desorption Behavior of Octanethiol Self-Assembled Monolayers: Cu, Ag, and Au. The Journal of Physical Chemistry C 2012, 116 (33), 17586-17593. DOI: 10.1021/jp3041204.

(120) Hayashi, T.; Tanaka, Y.; Koide, Y.; Tanaka, M.; Hara, M. Mechanism underlying bioinertness of self-assembled monolayers of oligo(ethyleneglycol)-terminated alkanethiols on gold: protein adsorption, platelet adhesion, and surface forces. Phys Chem Chem Phys 2012, 14 (29), 10196-10206. DOI: 10.1039/c2cp41236e  From NLM Medline.

(121) 田中賢; 林智広; 森田成昭. バイオ界面における水分子の役割は?-次世代医療を切り開く生体親和性材料-. 化学 2011, 66 (5), 68-69.

(122) Tamada, K.; Li, X.; Wulandari, P.; Nagahiro, T.; Michioka, K.; Toma, M.; Toma, K.; Obara, D.; Nakada, T.; Hayashi, T.; et al. Fabrication and Application of Plasmonic Silver Nanosheet; Springer, 2011.

(123) Hayashi, T.; Hara, M. Nonfouling self-assembled monolayers: mechanisms underlying protein and cell resistance. Current Physical Chemistry 2011, 1 (2), 90-98.

(124) Arai, Y.; Okabe, K.; Sekiguchi, H.; Hayashi, T.; Hara, M. Nanoscale chemical composition analysis using peptides targeting inorganic materials. Langmuir 2011, 27 (6), 2478-2483. DOI: 10.1021/la104178h  From NLM Medline.

(125) 林智広; 新井勇貴; 原正彦. 生体分子をプローブとした表面の化学組成分析. Molecular Electronics and Biolectronics 2010, 21 (2), 73-78.

(126) Nagahiro, T.; Ishibashi, K.; Kimura, Y.; Niwano, M.; Hayashi, T.; Ikezoe, Y.; Hara, M.; Tatsuma, T.; Tamada, K. Ag nanoparticle sheet as a marker of lateral remote photocatalytic reactions. Nanoscale 2010, 2 (1), 107-113. DOI: 10.1039/b9nr00240e  From NLM Medline.

(127) 林智広; 田中勇作; 原正彦. 生体分子の吸着忌避特性を持つ表面が引き起こすナノメートルスケールの相互作用. 表面科学 2009, 30, 444-447.

(128) Lee, S. Y.; Nakaya, K.; Hayashi, T.; Hara, M. Quantitative study of the gold-enhanced fluorescence of CdSe/ZnS nanocrystals as a function of distance using an AFM probe. Phys Chem Chem Phys 2009, 11 (21), 4403-4409. DOI: 10.1039/b819903e  From NLM PubMed-not-MEDLINE.

(129) LEE, S. Y.; Isoshima, T.; HAYASHI, T.; HARA, M. Blinking Kinetics of Single CdSe/ZnS Nanocrystals by Photon-Counting Statistics at High Temporal Resolution. e-Journal of Surface Science and Nanotechnology 2009, 7, 701-707.

(130) Hayashi, T.; Wakamatsu, K.; Ito, E.; Hara, M. Effect of Steric Hindrance on Desorption Processes of Alkanethiols on Au(111). The Journal of Physical Chemistry C 2009, 113 (43), 18795-18799. DOI: 10.1021/jp906494u.

(131) Hayashi, T.; Tanaka, Y.; Usukura, H.; Hara, M. Behavior of Hydroxide Ions in Vicinity of Self-Assembled Monolayers of Alkanethiols on Metals. e-Journal of Surface Science and Nanotechnology 2009, 7, 601-605.

(132) Hayashi, T.; Sano, K.; Shiba, K.; Iwahori, K.; Yamashita, I.; Hara, M. Critical amino acid residues for the specific binding of the Ti-recognizing recombinant ferritin with oxide surfaces of titanium and silicon. Langmuir 2009, 25 (18), 10901-10906. DOI: 10.1021/la901242q  From NLM Medline.

(133) Hayashi, T.; Makiuchi, N.; Hara, M. Self-Assembled Monolayers with Chemical Gradients: Fabrication and Protein Adsorption Experiments. Japanese Journal of Applied Physics 2009, 48 (9), 095503-095507. DOI: 10.1143/jjap.48.095503.

(134) 林智広; 熊谷悠記; 熊代善一; 齋藤公良; 原正彦. Au(111)表面上におけるシクロデキストリン末端基を持つチオール分子の吸着プロセス: 立体障害を持つ分子を高秩序配列させるためには. 表面科学 2008, 29 (8), 495-497.

(135) Otsuki, J.; Arai, Y.; Amano, M.; Sawai, H.; Ohkita, M.; Hayashi, T.; Hara, M. Superperiodic assembly of 2,6-diethynylpyridine through weak hydrogen bonds at the 1-phenyloctane/HOPG interface. Langmuir 2008, 24 (11), 5650-5653. DOI: 10.1021/la8003036  From NLM PubMed-not-MEDLINE.

(136) 林智広; 佐野健一; 芝清隆; 岩堀健治; 山下一郎; 原正彦. 原子間力顕微鏡を用いた無機物認識ペプチドのターゲット認識メカニズムの解明. 表面科学 2007, 28 (7), 391-396.

(137) 林智広. 金属薄膜標準物質の現状,ニーズ,技術背景に関する報告. AIST BULLETIN OF METROLOGY 2007, 6 (1), 61-68.

(138) Hayashi, T.; Tanaka, M.; Yamamoto, S.; Shimomura, M.; Hara, M. Direct observation of interaction between proteins and blood-compatible polymer surfaces. Biointerphases 2007, 2 (4), 119-125, Research Support, Non-U.S. Gov’t. DOI: 10.1116/1.2794712  From NLM PubMed-not-MEDLINE.

(139) 原正彦; Wang, T.; 林智広. 走査型プローブ顕微鏡の可能性. 生体の科学 2006, 57 (4), 287-291.

(140) Yamashita, I.; Kirimura, H.; Okuda, M.; Nishio, K.; Sano, K.; Shiba, K.; Hayashi, T.; Hara, M.; Mishima, Y. Selective nanoscale positioning of ferritin and nanoparticles by means of target-specific peptides. Small 2006, 2 (10), 1148-1152, Research Support, Non-U.S. Gov’t. DOI: 10.1002/smll.200600220  From NLM Medline.

(141) Nakamura, F.; Ito, E.; Hayashi, T.; Hara, M. Fabrication of COOH-terminated self-assembled monolayers for DNA sensors. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2006, 284-285, 495-498. DOI: 10.1016/j.colsurfa.2005.10.088.

(142) Hayashi, T.; Sano, K.; Shiba, K.; Kumashiro, Y.; Iwahori, K.; Yamashita, I.; Hara, M. Mechanism underlying specificity of proteins targeting inorganic materials. Nano Lett 2006, 6 (3), 515-519, Research Support, Non-U.S. Gov’t. DOI: 10.1021/nl060050n  From NLM Medline.

(143) Hayashi, T.; Hara, M. Long-Ranged and Short-Ranged Electrostatic Interaction Between Modified Silicon Surfaces and Recombinant Ferritin Molecules. Japanese Journal of Applied Physics 2005, 44 (7S), 5374-5377. DOI: 10.1143/jjap.44.5374.

(144) 栗原一嘉; 林智広; 原正彦. 吸光・蛍光材料の表面プラズモン分光法と電極界面への応用可能性. Review of Polarography 2004, 50 (3), 183.

(145) Schwendel, D.; Hayashi, T.; Dahint, R.; Pertsin, A.; Grunze, M.; Steitz, R.; Schreiber, F. Interaction of Water with Self-Assembled Monolayers:  Neutron Reflectivity Measurements of the Water Density in the Interface Region. Langmuir 2003, 19 (6), 2284-2293. DOI: 10.1021/la026716k.

(146) 森川良忠; 林智広; 劉子敬; 野副尚一. 金-チオール系自己組織化膜の第一原理分子動力学シミュレーション. 表面科学 2002, 23, 423-430.

(147) Pertsin, A. J.; Hayashi, T.; Grunze, M. Grand Canonical Monte Carlo Simulations of the Hydration Interaction between Oligo(ethylene glycol)-Terminated Alkanethiol Self-Assembled Monolayers. The Journal of Physical Chemistry B 2002, 106 (47), 12274-12281. DOI: 10.1021/jp025747l.

(148) Morikawa, Y.; Hayashi, T.; Liew, C. C.; Nozoye, H. First-principles theoretical study of alkylthiolate adsorption on Au(111). Surface Science 2002, 507-510, 46-50. DOI: 10.1016/s0039-6028(02)01173-1.

(149) Hayashi, T.; Pertsin, A. J.; Grunze, M. Grand canonical Monte Carlo simulation of hydration forces between nonorienting and orienting structureless walls. The Journal of Chemical Physics 2002, 117 (13), 6271-6280. DOI: 10.1063/1.1504436.

(150) Pertsin, A. J.; Hayashi, T.; Grunze, M. The interaction of oligo(ethylene glycol) with water: Testing an atomistic force field for transferability. Physical Chemistry Chemical Physics 2001, 3 (9), 1598-1601. DOI: 10.1039/b100097g.

(151) Kodama, C.; Hayashi, T.; Nozoye, H. Decomposition of alkanethiols adsorbed on Au (1 1 1) at low temperature. Applied Surface Science 2001, 169-170, 264-267. DOI: 10.1016/s0169-4332(00)00664-4.

(152) Hayashi, T.; Morikawa, Y.; Nozoye, H. Adsorption state of dimethyl disulfide on Au(111): Evidence for adsorption as thiolate at the bridge site. The Journal of Chemical Physics 2001, 114 (17), 7615-7621. DOI: 10.1063/1.1360245.

(153) Hayashi, T.; Kodama, C.; Nozoye, H. Structural evolution of dibutyldisulfide adsorbed on Au(111). Applied Surface Science 2001, 169-170, 100-103. DOI: 10.1016/s0169-4332(00)00647-4.

(154) Hayashi, T.; Fricke, A.; Katsura, K.; Kodama, C.; Nozoye, H. Adsorption state of diethyldisulfide on Au(111) studied with a combined system of HREELS and STM. Surface Science 1999, 427-428, 393-397. DOI: 10.1016/s0039-6028(99)00308-8.

(155) 鈴木克己; 六田英治; 林智広; 伊藤淳; 大島忠平; 櫻井利夫. Ni (111) 上の六方晶系窒化ホウ素膜の安定性. 真空 1998, 41 (3), 399.