[paper accepted] Mechanical properties and hydration of zwitterionic peptide SAMs

Using quartz crystal microbalance with dissipation monitoring (QCM-D), we investigated the assembly, viscoelastic properties and interfacial hydration of zwitterionic peptide SAMs with four sequences (EK, DK, ER and DR). Arginine-containing SAMs showed a higher apparent elastic modulus and viscosity than the lysine-containing ones, highlighting the role of amino acid composition in these antifouling coatings.

Junsong Hu, Glenn Villena Latag, Zhentao Zhao, Shoichi Maeda, Kasumi Tsuji, Tomohiro Hayashi. “Evaluation of the Mechanical Properties of Zwitterionic Peptide Self-Assembled Monolayers and Their Interfacial Hydration via a Quartz Crystal Microbalance with Dissipation Monitoring”. ACS Applied Bio Materials (2026).